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Buffalo’s opponents for the 2021 NFL season have been finalized

The Bills opponents in 2021 will feature the AFC South and the NFC South based on the league’s rotational schedule.

The intra-conference matchups based on order of finish has the Bills playing the AFC West winners the Kansas City Chiefs on the road and the AFC North winners the Pittsburgh Steelers at home.

Like every year, Buffalo will play their AFC East rivals once at home and once on the road.

Here is the list of Buffalo’s home and away opponents for next season.




  • Indianapolis Colts
  • Pittsburgh Steelers
  • Houston Texans
  • Atlanta Falcons
  • Carolina Panthers
  • Miami Dolphins
  • New England Patriots
  • New York Jets



  • Kansas City Chiefs
  • Jacksonville Jaguars
  • Tennessee Titans
  • New Orleans Saints
  • Tampa Bay Buccaneers
  • Miami Dolphins
  • New England Patriots
  • New York Jets