Week 16 of the NFL season is here, and the Buffalo Bills will travel to Cleveland to face the Browns for their final road game of the regular season today at 1 p.m.
Buffalo (10-4) comes in riding a three-game win streak, including a thrilling 35-31 comeback over the New England Patriots, erasing a 21-point first-half deficit to keep their AFC East hopes alive heading into the final three weeks. Cleveland (3-11), meanwhile, suffered a lopsided 31-3 loss to the Chicago Bears, marking their sixth defeat in seven games.
This will be the 25th meeting between the Bills and Browns. The most recent matchup came in 2022, when Buffalo won 31-23 in Detroit after the game was relocated from Buffalo due to a snowstorm. The Bills have not played in Cleveland since a 19-16 loss in 2019, when Josh Allen faced Baker Mayfield, and Buffalo has not won a game in Cleveland since 2012.
GAME WEEK LINKS
- Top 5 storylines for Bills at Browns | Week 16 (BuffaloBills.com)
- Buffalo Bills at Cleveland Browns Week 16 odds, spread, betting info (BuffaloRumblings.com)
- Bills aim for early knockout in Cleveland with playoff clock ticking (D&C.com)
- Bills vs. Browns | Weekly notes, quotes and stats before Week 16 matchup (BuffaloBills.com)
- Bills vs. Browns injury update: Two Buffalo starters could return (D&C.com)
- Christian Benford provides insight on injury ahead of Buffalo Bills’ game vs. Browns (SI.com)
- How the Buffalo Bills can clinch a playoff berth in Week 16 | 2025 (BuffaloBills.com)
- Bills have golden opportunity to exploit Shedeur Sanders, Browns’ weakness in Week 16 (SI.com)
- Bills news: Get to know Buffalo’s Week 16 replacement for Matt Prater (BuffaloRumblings.com)
- Josh Allen jokes about potentially being on wrong side of history vs. Browns (SI.com)
- Bills tackle has the perfect response to possibly giving up the NFL sack record to Myles Garrett (Syracuse.com)
- Buffalo Bills injury report vs. Browns | Week 16 (BuffaloBills.com)
- AFC playoff standings, Bills’ rooting guide in Week 16 (BillsWire.com)
- Buffalo Bills activate wide receiver Mecole Hardman Jr., elevate K Michael Badgley and DE Andre Jones Jr. (BuffaloBills.com)
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Kyle leads sports coverage and hosts the Concrete Jungle podcast. Have a lead or question? Send it to [email protected].