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It may now be possible to detect bone loss in premenopausal woman

A new study has found that physicians may now be able to detect if menopause-related bone loss is starting to happen by measuring a hormone called anti-Mullerian. This hormone declines as a woman reaches their final menstrual period. The findings, published in the Journal of Bone and Mineral Research, could help doctors identify which premenopausal women are at risk for developing osteoporosis later in life and may need to be treated with bone-building medications.

Osteoporosis is a condition characterized by thinning of the bones, leading to fractures. It affects an estimated 200 million women worldwide and is a significant public health concern, particularly for postmenopausal women. While osteoporosis can occur at any age, the condition is most common in older adults. There’s more information about osteoporosis on this page

There are several risk factors for osteoporosis, including being female, having a family history of the condition, and being of Caucasian or Asian descent. However, the exact cause of osteoporosis is unknown.

The new study looked at data from women about the age of 42 years and above. The researchers measured the anti-Mullerian hormone (AMH) levels in blood samples from these women. AMH levels were found to be significantly lower in women who had gone through menopause compared to those who had not.

The findings suggest that measuring AMH levels could potentially screen for osteoporosis risk in premenopausal women. The researchers say that further studies are needed to confirm these results.

Bone loss tends to happen a year before a woman’s last menstrual period, setting the stage for osteoporosis. This makes early detection and treatment crucial for preventing the condition. These include lifestyle changes, such as getting enough calcium and vitamin D and medications.

According to researchers who studied the data from the Study of Women’s Health Across the Nation. They found that roughly 17 percent of premenopausal women will lose a significant portion of their peak bone mass during the last few years before menopause. 


Reducing the Risk of Bone Loss During Menopause

There are many things that women can do to reduce their risk of bone loss during menopause. Here are some tips:

  1. Get regular exercise – Exercise is essential for maintaining bone health at any age, but it becomes even more important during and after menopause. The loss of estrogen during menopause can lead to a decrease in bone density, which can lead to an increased risk of fractures. However, exercise can help offset this loss of bone density by stimulating the production of new bone cells. Weight-bearing exercises, in particular, can help to strengthen bones and reduce the risk of fractures. In addition, exercise can also help improve balance and coordination, which can further reduce the risk of falls and fractures. As a result, regular exercise is an integral part of maintaining bone health during and after menopause.
  2. Eat a healthy diet. Women can do things to help protect their bones, including getting enough calcium and vitamin D. Calcium is essential for strong bones, and vitamin D helps the body absorb calcium. A diet rich in both of these nutrients can help slow down bone loss and prevent osteoporosis. So if you’re approaching menopause, be sure to add plenty of calcium-rich foods like dairy products and leafy greens.
  3. Quit smoking. Smoking cigarettes is known to have numerous negative impacts on health, ranging from an increased risk of cancer to respiratory problems. However, few people know that smoking can also lead to bone loss and osteoporosis. Studies have shown that smokers are more likely to suffer from bone fractures, particularly hip and spine. This is because smoking decreases the body’s ability to absorb calcium, which is essential for strong bones. In addition, smoking causes a decrease in blood flow, leading to bone loss. Quitting smoking can help to reduce the risk of osteoporosis, as well as other health problems. While quitting may be challenging, the benefits are well worth the effort.
  4. Limit alcohol intake. While moderate alcohol consumption has been linked to health benefits such as reduced risk of heart disease and stroke, excessive drinking can have serious consequences for the body, including bone loss. Alcohol interferes with the absorption of calcium and other nutrients that are essential for bone health. Additionally, it increases the production of a hormone that breaks down bone tissue. Over time, this can lead to osteoporosis, a condition characterized by weak and fragile bones. Women are especially vulnerable to the effects of excessive alcohol consumption on bone health due to their more diminutive stature and lower levels of testosterone. Therefore, it is important to drink alcohol in moderation to protect your bones and maintain your overall health.
  5. Get enough sleep. Sleep helps the body to repair and rebuild itself, including bones.
  6. Take bone-building supplements. Supplements such as calcium and vitamin D can help to prevent bone loss.
  7. Get regular checkups. Having regular checkups with your doctor can help to identify any potential health problems early on.
  8. Talk to your doctor about hormone replacement therapy. Hormone replacement therapy can help to reduce the risk of bone loss in menopausal women by providing the right hormones for your body.



There are many things women can do to reduce their risk of bone loss during menopause. What matters is going into a strict regime. If you come at a certain age, ask your doctor if you are at risk for bone loss. They may have certain tests that may help determine it for you.


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