The Buffalo Bills return to Highmark Stadium today for a marquee Week 17 matchup, hosting the Philadelphia Eagles at 4:25 p.m. in Buffalo’s second-to-last home game of the regular season. The Bills enter at 11-4, riding a four-game win streak, while the Eagles are 10-5.
This marks the 16th all-time meeting between the franchises and the first time Philadelphia has played in Buffalo since 2019. The Bills are also seeing the Eagles for the first time since a dramatic 2023 overtime loss, part of a recent stretch that hasn’t favored Buffalo. The Bills’ last win in the series came back in 2011. Josh Allen, meanwhile, is still searching for his first career victory against Philadelphia, sitting at 0-2, though he owns an impressive 27-8 record against NFC opponents overall.
Allen enters this matchup on the verge of history, needing one touchdown to become the youngest and fastest player in NFL history to reach 300 regular-season touchdowns.
The Bills are also looking to reach the 12-win mark for the fourth time in six seasons.
GAME WEEK LINKS
- Top 5 storylines for Bills vs. Eagles | Week 17 (BuffaloBills.com)
- Bills vs Eagles predictions, keys to game as Highmark era nears its end (D&C.com)
- Bills vs. Eagles: 5 things to watch for during Week 17 game (BillsWire.com)
- What channel is Bills-Eagles game on? Start time, how to watch NFL Week 17 (D&C.com)
- Buffalo Bills injury report vs. Eagles | Week 17 (BuffaloBills.com)
- Josh Allen-Jalen Hurts matchup will be NFL first during Bills vs. Eagles in Week 17 (SI.com)
- Buffalo Bills announce Paul Posluszny as Legend of the Game for Week 17 game against the Eagles (BuffaloBills.com)
- Buffalo Bills starting DT’s status problematic for Week 17 vs. Eagles (SI.com)
- AFC Playoff Picture — Who Buffalo Bills fans should root for in Week 17 | 2025 (BuffaloBills.com)
- Bills part ways with WR Mecole Hardman after brief stint (FingerLakes1.com)

